BDBM288187 8-Chloro-5-(7-chloro-1H-indazol-5-yl)-2,6-bis(trifluoromethyl)-::US10087185, Example 5

SMILES FC(F)(F)c1nc2c(Cl)cc(c(-c3cc(Cl)c4[nH]ncc4c3)n2n1)C(F)(F)F

InChI Key InChIKey=VYJHXNWOAKYBKY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 288187   

TargetVoltage-dependent calcium channel gamma-8 subunit(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM288187(US10087185, Example 5 | 8-Chloro-5-(7-chloro-1H-in...)
Affinity DataIC50: 0.316nMpH: 7.4Assay Description:This assay was used to test compounds for their ability to inhibit TARP γ8 dependent AMPA receptor activity. The AMPA receptor is a non-selectiv...More data for this Ligand-Target Pair
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Date in BDB:
1/17/2019
Entry Details
US Patent