BDBM28991 (2R)-2-{[5-chloro-2-(hydroxymethyl)phenyl](4-chlorobenzene)sulfonamido}propyl N-methylcarbamate::Carbamate-appended N-alkylsulfonamide, 12
SMILES CNC(=O)OC[C@@H](C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=ANCQOSJSIUWCQF-GFCCVEGCSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 28991
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataEC50: 15nMAssay Description:H4 human neuroglioma cells expressing beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced with the conditioned...More data for this Ligand-Target Pair