BDBM290533 US10099993, Compound 114::US10099993, Compound 121

SMILES Cc1c(C)c(ccc1OCc1cccc(COc2ccc(\C=C\C(O)=O)c(O)c2)c1)C(=O)CC1CCCC1

InChI Key InChIKey=UWNZWLBEERGDKO-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 290533   

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290533(US10099993, Compound 114 | US10099993, Compound 12...)
Affinity DataEC50: >3.00E+4nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 3(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290533(US10099993, Compound 114 | US10099993, Compound 12...)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 2(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290533(US10099993, Compound 114 | US10099993, Compound 12...)
Affinity DataEC50: >3.00E+4nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent

TargetMetabotropic glutamate receptor 3(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM290533(US10099993, Compound 114 | US10099993, Compound 12...)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
US Patent