BDBM29233 CHEMBL508014::aminopyridine-pyrrolidine, 5
SMILES NCCN[C@@H]1CNC[C@@H]1Cc1cccc(N)n1
InChI Key InChIKey=BETYXZSFUFTOLC-GXSJLCMTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 29233
Affinity DataKi: 388nM ΔG°: -8.89kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
Affinity DataKi: 388nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 388nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
Affinity DataKi: 388nMAssay Description:Inhibition of recombinant rat nNOS overexpressed in Escherichia coli using L-arginine as substrate assessed as NO production by hemoglobin capture as...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N,M336V](Rattus norvegicus (rat))
University of California Irvine
University of California Irvine
Affinity DataKi: 3.67E+4nM ΔG°: -6.15kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University
Curated by ChEMBL
Northwestern University
Curated by ChEMBL
Affinity DataKi: 5.84E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.84E+4nMAssay Description:Inhibition of rat recombinant nNOSMore data for this Ligand-Target Pair
Affinity DataKi: 4.17E+5nM ΔG°: -4.69kcal/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
Affinity DataKi: 4.35E+5nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
Affinity DataKi: 4.35E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair