BDBM29277 CHEMBL451332::sulfonamide, 3

SMILES NS(=O)(=O)c1ccc(CCC(O)=O)cc1

InChI Key InChIKey=JUEONDBIBADVGD-UHFFFAOYSA-N

Data  17 KI

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 29277   

TargetCarbonic anhydrase(Saccharomyces cerevisiae)
Balikesir University

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  165nMAssay Description:Inhibition of Saccharomyces cerevisiae recombinant CA expressed in Escherichia coli by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  256nMAssay Description:Inhibition of cloned Stylophora pistillata alpha-CA expressed in human HEK293 cells by stopped-flow CO2 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  256nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  294nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
Universite Degli Studi Di Firenze

LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  440nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  495nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  495nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  495nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  495nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec by stopped-flow methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Centre Scientifique De Monaco

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  495nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Candida albicans (Yeast))
Universite Degli Studi Di Firenze

LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  1.28E+3nM ΔG°:  -7.90kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Balikesir University

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  6.69E+3nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Balikesir University

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  6.69E+3nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Balikesir University

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  6.69E+3nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Kochi Medical School

LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  7.83E+3nM ΔG°:  -6.84kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Kochi Medical School

LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  7.93E+3nM ΔG°:  -6.84kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Universit£

Curated by ChEMBL
LigandPNGBDBM29277(CHEMBL451332 | sulfonamide, 3)
Affinity DataKi:  2.84E+4nMAssay Description:Inhibition of full length Mycobacterium tuberculosis H37Rv recombinant carbonic anhydrase 2 encoded by RV3588c by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed