BDBM292983 9-(1-Fluoro-2-morpholinoethyl)-6-(4-methoxybenzyl)pyrido[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5(6H)-one::US10105367, Example 269::US10376514, Example 269

SMILES COc1ccc(Cn2c3ncc(cc3c3ncnn3c2=O)C(F)CN2CCOCC2)cc1

InChI Key InChIKey=JNCPBIHAQORAFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 292983   

LigandPNGBDBM292983(US10105367, Example 269 | 9-(1-Fluoro-2-morpholino...)
Affinity DataIC50: 550nMAssay Description:The selectivity of compounds of the present invention was determined using a panel of recombinant human PDEs and an in vitro enzymatic assay (BPS Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details
US Patent

LigandPNGBDBM292983(US10105367, Example 269 | 9-(1-Fluoro-2-morpholino...)
Affinity DataIC50: 550nMT: 2°CAssay Description:PDE1B inhibition was determined by an IMAP TR-FRET assay. The IMAP TR-FRET PDE assay was optimized for concentration of enzyme, Calmodulin, cAMP or c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2019
Entry Details
US Patent