BDBM29394 CHEMBL220294::tacrine-dihydropyridine hybrid (tacripyrine), 5
SMILES CCOC(=O)C1C(c2cccc(c2)[N+]([O-])=O)c2c(N)c3CCCCc3nc2N=C1C
InChI Key InChIKey=QHRIUVOIKYNLOD-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 29394
Affinity DataIC50: 191nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards hAChE was determined following the method of Ellman using AChE from human serum and acetylthiocholin...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the compounds towards BuChE was determined following the method of Ellman using BuChE from human serum and butyrylthiochol...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of Electrophorus electricus AChEMore data for this Ligand-Target Pair
Affinity DataIC50: 191nMAssay Description:Inhibition of human erythrocyte AChEMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human serum BuChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Laboratorio De Radicales Libres (Iqog, Csic)
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:The inhibitory activity of the compounds towards AChE was determined following the spectrophotometric method of Rappaport using purified AChE from Ee...More data for this Ligand-Target Pair