BDBM296087 2-(1-benzyl-1H-indazol-5-yloxy)- pyridino[3,4-d]pyrimidin-4-ol::US10112940, Example 15::US10208039, Example 15::US10611763, Example 15::US10815234, Example 15::US11535616, Example 15

SMILES Oc1nc(Oc2ccc3n(Cc4ccccc4)ncc3c2)nc2cnccc12

InChI Key InChIKey=AYNNEVPMDRKQCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 296087   

TargetLysine-specific demethylase 4C(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM296087(US10112940, Example 15 | 2-(1-benzyl-1H-indazol-5-...)
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2019
Entry Details
US Patent