BDBM297159 US10112941, Example 275

SMILES COc1cc(cc2n([C@@H](C3CCOCC3)c3ccc(F)cc3)c3cc(cnc3c12)-c1c(C)nnn1C)C(C)(C)O

InChI Key InChIKey=FYIRLSRQZUHAEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 297159   

TargetBromodomain-containing protein 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM297159(US10112941, Example 275)
Affinity DataIC50: 5nMAssay Description:All assay components were dissolved in buffer composition 20 mM Hepes pH 7.5, 150 mM NaCl, 5 mM DTT, 0.005% Tween 20, and 100 ug/ml BSA for BRD4 (1-4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent