BDBM297392 US10112968, Compound SAH

SMILES N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)OC=O

InChI Key InChIKey=HIGCALLWUWOHCV-BAYCTPFLSA-N

Data  1 KI  1 Kd  1 Koff  1 Kon

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 297392   

TargetHistone-lysine N-methyltransferase, H3 lysine-79 specific(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM297392(US10112968, Compound SAH)
Affinity DataKi:  320nM Kd:  71nM Kon:  0.100M-1s-1 Koff:  1.40E+6s-1Assay Description:Unless otherwise indicated, assays of DOT1L enzymatic activity were performed under balanced conditions (all substrates present at concentrations equ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent