BDBM297654 Methyl 2-(2-cyclopropyl-4-(4-(2- methoxyphenyl)piperidin-1-yl)-6- methylpyrimidin-5-yl)acetate::US10118902, Example 156::US10584103, Example 156

SMILES COC(=O)Cc1c(C)nc(nc1N1CCC(CC1)c1ccccc1OC)C1CC1

InChI Key InChIKey=OCKLGPSZZYPSGA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 297654   

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297654(US10118902, Example 156 | Methyl 2-(2-cyclopropyl-...)
Affinity DataEC50: >1.00E+4nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 uL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 at a c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetNeurotensin receptor type 1(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM297654(US10118902, Example 156 | Methyl 2-(2-cyclopropyl-...)
Affinity DataEC50: >1.00E+4nMAssay Description:NTSR1 (NTR1) CHO cells are plated in 20 μL of assay media containing Ham's F12 supplemented with 10% fetal bovine serum and 0.4 mg/mL G418 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2020
Entry Details
US Patent