BDBM298062 3-[4-(2-methylphenyl)-1,3-thiazol-2-yl]-7-(piperidin-4-yl)pyrazolo[1,5-c]pyrimidin-5(4H)-one hydrochloride::US10118930, Example 273::US10118930, Example 448

SMILES Cc1ccccc1-c1csc(-c2cnn3c(C4CCNCC4)cc(=O)[nH]c23)n1

InChI Key InChIKey=PVFFPOQOEANRPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 298062   

TargetTissue-type plasminogen activator(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 298062BDBM298062(US10118930, Example 448 | 3-[4-(2-methylphenyl)-1,...)
Affinity DataIC50: 27nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetTissue-type plasminogen activator(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 298062BDBM298062(US10118930, Example 448 | 3-[4-(2-methylphenyl)-1,...)
Affinity DataIC50: 30nMAssay Description:The clot-lysis test system configures the kinetics of clot formation and degradation in vitro and allows quantifying modulation of the process by sel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent