BDBM299390 US9593129, Example 66

SMILES CC[C@H](N1[C@@H]([C@H](C[C@@](C)(CC(O)=O)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1)C(=O)OC(C)(C)C

InChI Key InChIKey=BTIJKFCQUAULPU-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 299390   

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandChemical structure of BindingDB Monomer ID 299390BDBM299390(US9593129, Example 66)
Affinity DataIC50: 310nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2019
Entry Details
US Patent