BDBM299525 6-[3-(4-methyl- 1,2,4-triazol-3-yl)- 1-piperidyl]pyrido [3,2-d]pyrimidin- 4-amine::US9592235, Example 298::US9855269, Compound 145

SMILES Cn1cnnc1C1CCCN(C1)c1ccc2ncnc(N)c2n1

InChI Key InChIKey=ZHDTYIAPZYLYJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299525   

LigandPNGBDBM299525(US9592235, Example 298 | 6-[3-(4-methyl- 1,2,4-tri...)
Affinity DataIC50: 3.20E+3nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

LigandPNGBDBM299525(US9592235, Example 298 | 6-[3-(4-methyl- 1,2,4-tri...)
Affinity DataIC50: 3.20E+3nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent