BDBM29986 arylpyrazole, 31

SMILES Cc1c(CN[C@H]2CC[C@@H](F)C2)nn(c1-c1cnc(C)c(F)c1)-c1ncccc1Cl

InChI Key InChIKey=CTNODSDKBPJKAA-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 29986   

TargetNociceptin receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29986(arylpyrazole, 31)
Affinity DataIC50: 0.310nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29986(arylpyrazole, 31)
Affinity DataIC50: 0.520nM EC50:  0.310nMAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM29986(arylpyrazole, 31)
Affinity DataIC50: 0.520nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from ORL1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
LigandPNGBDBM29986(arylpyrazole, 31)
Affinity DataIC50: 4.10E+4nMAssay Description:Compounds were tested for their inhibitory effects on ligand binding to the human ORL1 receptor. Bound and free radioligands are separated by filtra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2009
Entry Details Article
PubMed