BDBM300629 6-(3-fluorophenyl)-N-[3-({2- [(1S,4S)-2-oxa-5- azabicyclo[2.2.1]hept-5- yl]propanoyl}amino)-4- (trifluoromethoxy)phenyl] nicotinamide::US10130633, Example 199

SMILES CC(C(=O)Nc3cc(NC(=O)c2ccc(c1cccc(F)c1)nc2)ccc3OC(F)(F)F)N4C[C@@H]5C[C@H]4CO5

InChI Key InChIKey=IUQPGUXQWQGVHA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300629   

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300629(6-(3-fluorophenyl)-N-[3-({2- [(1S,4S)-2-oxa-5- aza...)
Affinity DataIC50: 71.7nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300629(6-(3-fluorophenyl)-N-[3-({2- [(1S,4S)-2-oxa-5- aza...)
Affinity DataIC50: 8.80E+3nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent