BDBM300617 6-(3,5-difluorophenyl)-N-[3-{[2- (morpholin-4- yl)propanoyl]amino}-4- (trifluoromethoxy)phenyl] nicotinamide::BDBM300633::US10130633, Example 187

SMILES CC(N1CCOCC1)C(=O)Nc1cc(NC(=O)c2ccc(nc2)-c2cc(F)cc(F)c2)ccc1OC(F)(F)F

InChI Key InChIKey=KHTVKLOEOYGTGS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 300617   

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300617(US10130633, Example 187 | 6-(3,5-difluorophenyl)-N...)
Affinity DataIC50: 124nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300617(US10130633, Example 187 | 6-(3,5-difluorophenyl)-N...)
Affinity DataIC50: 175nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300617(US10130633, Example 187 | 6-(3,5-difluorophenyl)-N...)
Affinity DataIC50: 1.52E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300617(US10130633, Example 187 | 6-(3,5-difluorophenyl)-N...)
Affinity DataIC50: 4.20E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent