BDBM300643 6-(2-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)propanoyl]amino}-4- (trifluoromethoxy)phenyl] nicotinamide::US10130633, Example 213

SMILES CC(C(=O)Nc3cc(NC(=O)c2ccc(c1ccccc1F)nc2)ccc3OC(F)(F)F)N4CCOCC4

InChI Key InChIKey=XFZOXFOCQJSZKQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300643   

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300643(6-(2-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)prop...)
Affinity DataIC50: 140nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent

TargetProtein Wnt-3a(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM300643(6-(2-fluorophenyl)-N-[3-{[2- (morpholin-4- yl)prop...)
Affinity DataIC50: 5.00E+4nMAssay Description:In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
Go to US Patent