BDBM301830 US9598387, Compound 16::US9969743, 16

SMILES CC(C)(C)c1nc(cc(n1)C(F)(F)F)N1CCN(CCCCNC(=O)N2CCC(CC2)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=IBWTYJNEHLEZKF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 301830   

TargetD(3) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM301830(US9598387, Compound 16 | US9969743, 16)
Affinity DataKi:  21.2nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetD(3) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM301830(US9598387, Compound 16 | US9969743, 16)
Affinity DataKi:  21.2nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM301830(US9598387, Compound 16 | US9969743, 16)
Affinity DataKi:  894nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetD(2) dopamine receptor(Human)
Southern Research Institute

US Patent
LigandPNGBDBM301830(US9598387, Compound 16 | US9969743, 16)
Affinity DataKi:  894nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2020
Entry Details
US Patent