BDBM303501 US10138229, Example 9::US10875852, Example 9

SMILES NC(=O)c1cn(nc1-c1ccc(Cc2ccccc2)cc1)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=GZYPOPVJARKJLO-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303501   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303501(US10138229, Example 9 | US10875852, Example 9)
Affinity DataIC50:  14nMAssay Description:An HTRF assay (Cisbio KinEASE-TK cat #62TK0PEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303501(US10138229, Example 9 | US10875852, Example 9)
Affinity DataIC50:  14nMAssay Description:TBDAn HTRF assay (Cisbio KinEASE-TK cat #62TKOPEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent