BDBM303811 2-(11′-Chloro-2′,5′-dioxo-2′,5′,6′,8′-tetrahydro-3′H-spiro[cyclopropane-1,7′-pyrido[3,4-e][3]benzazocine]-3′-yl)-N-(2-oxo-2,3-dihydro-1H-benzimidazol-5-yl)-3-phenylpropanamide (Stereoisomer Mixture)::US10138236, Example 29
SMILES Clc1ccc2CC3(CC3)NC(=O)c3cn(C(Cc4ccccc4)C(=O)Nc4ccc5[nH]c(=O)[nH]c5c4)c(=O)cc3-c2c1
InChI Key InChIKey=VUHILQGABHYBOA-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 303811
Affinity DataIC50: 42nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair