BDBM304160 USRE47141, Example 142

SMILES CN(Cc1nc(c([nH]1)-c1cccc(C)n1)-c1ccc2ncnn2c1)c1cccc(c1)C(N)=O

InChI Key InChIKey=UQWZXYPYOVHPBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304160   

TargetTGF-beta receptor type-1(Human)
Ewha University—Industry Collaboration Foundation

US Patent
LigandPNGBDBM304160(USRE47141, Example 142)
Affinity DataIC50: 153nMAssay Description:ALK5 protein was expressed in Sf9 insect cells as human recombinant GST-fusion protein using the baculovirus expression system. Expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent