BDBM304553 (R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((S)-1-(4-(trifluoromethyl)phenyl)ethyl)piperazine::US10144715, Compound 46-17::US10144715, Compound 46-19

SMILES CC(N1CCN(C[C@H]1c1ccccc1)c1cccc(c1)S(C)(=O)=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=DJPSHUCKIYCLKV-BIAFCPFJSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 304553   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304553((R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((S)-1...)
Affinity DataKi:  1.90E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304553((R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((S)-1...)
Affinity DataKi: >2.50E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304553((R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((S)-1...)
Affinity DataKi: >3.33E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM304553((R)-4-(3-(methylsulfonyl)phenyl)-2-phenyl-1-((S)-1...)
Affinity DataKi: >3.33E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent