BDBM304979 3-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)-3-(4-methyl-3-((5-methyl-1,1-dioxido-4,5-dihydrobenzo[f][1,2,5]thiadiazepin-2(3H)-yl)methyl)phenyl)propanoic acid::US10144731, Example 86

SMILES CN1CCN(Cc2cc(ccc2C)C(CC(O)=O)c2ccn(C)c(=O)c2)S(=O)(=O)c2ccccc12

InChI Key InChIKey=BTPDPSLUOKOLFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304979   

TargetKelch-like ECH-associated protein 1 [321-609](Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 304979BDBM304979(US10144731, Example 86 | 3-(1-methyl-2-oxo-1,2-dih...)
Affinity DataIC50: 550nMAssay Description:100 nL of 100× compound dose response curves (serial 3-fold dilutions) in DMSO are stamped using an Echo liquid handling system (Labcyte) into 384-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent