BDBM304986 3-(4-chloro-3-((5-methyl-1,1-dioxido-4,5-dihydrobenzo[f][1,2,5]thiadiazepin-2(3H)-yl)methyl)phenyl)-3-(1-methyl-1H-benzo[d][1,2,3]triazol-5-yl)propanoic acid::US10144731, Example 142

SMILES CN1CCN(Cc2cc(ccc2Cl)C(CC(O)=O)c2ccc3n(C)nnc3c2)S(=O)(=O)c2ccccc12

InChI Key InChIKey=WMFNTTPHZCWVFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304986   

TargetKelch-like ECH-associated protein 1 [321-609](Human)
Glaxosmithkline

US Patent
LigandChemical structure of BindingDB Monomer ID 304986BDBM304986(US10144731, Example 142 | 3-(4-chloro-3-((5-methyl...)
Affinity DataIC50: 550nMAssay Description:10-point semi-log dilution curves in DMSO are prepared in 96-well polypropylene plates to 100× final assay concentration. Compound curves are then di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent