BDBM305 (2R,3R)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-[(2S,3R)-4-[(2S)-2-(tert-butylcarbamoyl)-4-(3-phenylcyclobutyl)piperazin-1-yl]-3-hydroxy-1-phenylbutan-2-yl]carbamate::1-(2OHPr)-4-Substit-piperazine, thienyl carbamate deriv. 16

SMILES CC(C)[C@@H]1[C@@H](CCS1(=O)=O)OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN1CCN(C[C@H]1C(=O)NC(C)(C)C)C1CC(C1)c1ccccc1

InChI Key InChIKey=CZFIMHWLICRIED-AAYATXMLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 305   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM305((2R,3R)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50:  3.80nMAssay Description:Tested in vitro for the ability to inhibit HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM305((2R,3R)-1,1-dioxo-2-(propan-2-yl)--thiolan-3-yl N-...)
Affinity DataIC50:  3.80nMAssay Description:Sensitivity of HIV-1 protease activity to protease inhibitors was determined by a peptide substrate cleavage assay. Protease products were analyzed o...More data for this Ligand-Target Pair
In DepthDetails Article