BDBM308058 US10011593, Ex. 9::US9650366, 9
SMILES Cc1ccoc1C(=O)Nc1cccc(c1)C#Cc1cncc(c1)-c1nnn(CCCO)n1
InChI Key InChIKey=OGVARLFWIBVKET-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 308058
Affinity DataKi: 5nMAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:1) in 10...More data for this Ligand-Target Pair
Affinity DataKi: 21nMAssay Description:Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, pH 7.2...More data for this Ligand-Target Pair
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataKi: 1.00E+4nMAssay Description:Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu-Tyr (4:1) in...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:PDGFRβ: Biochemical PDGFRβ kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg of poly-Glu...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:VEGFR2: Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 μg/well of poly-Glu-Tyr (4:...More data for this Ligand-Target Pair
TargetInterferon-induced, double-stranded RNA-activated protein kinase(Homo sapiens (Human))
Allergan
US Patent
Allergan
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:PKR: Commercially available recombinant human GST-PKR (SignalChem, Canada; 1.5 uM-2 uM stock) is diluted to 500 nM in assay buffer (20 mM Tris-HCl, p...More data for this Ligand-Target Pair