BDBM308192 US9649309, Compound UNC2546A

SMILES CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1ccc(CNCCO)cn1

InChI Key InChIKey=NLXWFBBYANWXPR-WEBLMRDCSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 308192   

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308192(US9649309, Compound UNC2546A)
Affinity DataIC50:  0.810nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308192(US9649309, Compound UNC2546A)
Affinity DataIC50:  3.80nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308192(US9649309, Compound UNC2546A)
Affinity DataIC50: <10nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetGrowth arrest-specific protein 6(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308192(US9649309, Compound UNC2546A)
Affinity DataIC50:  20nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM308192(US9649309, Compound UNC2546A)
Affinity DataIC50:  69nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent