BDBM309952 N-(1H-benzo[d]- imidazol-5-yl)-2-(4- fluoro-phenyl)- pyrrolidine-1-carbo- thioamide::US9656991, 66

SMILES Fc1ccc(C2CCCN2C(=S)Nc2ccc3[nH]cnc3c2)cc1

InChI Key InChIKey=GRHKOAGEBQVIHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 309952   

TargetGlutaminyl-peptide cyclotransferase(Human)
Probiodrug

US Patent
LigandChemical structure of BindingDB Monomer ID 309952BDBM309952(US9656991, 66 | N-(1H-benzo[d]- imidazol-5-yl)-2-(...)
Affinity DataIC50: 1.28E+5nMAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent