BDBM311174 US10155731, Example 305

SMILES CCc1nc(cc2n(CCCOC)cc(c12)C(F)(F)F)[C@@H](C)N(C1CC1)C(=O)[C@H]1CNCCO1

InChI Key InChIKey=RGUSPKQQTQMWDZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 311174   

TargetRenin(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 311174BDBM311174(US10155731, Example 305)
Affinity DataIC50: 12nMAssay Description:A substrate of synthetic peptide (Nma-KHPFH LVIHK(Dnp)-NH2) and test compound were mixed, and fluorescence intensity was assayed using a fluorophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent