BDBM311342 (S)-1-((2′,5-bis(difluoromethyl)-[3,4′-bipyridin]-6-yl)oxy)-2,4-dimethylpentan-2-amine::US10155760, Example 199::US10351563, Example 199::US10544120, Example 199::US10723734, Example 199::US10981910, Example 199::US9902722, Example 199

SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)F)-c1ccnc(c1)C(F)F

InChI Key InChIKey=VNNGZCQZRNCYHO-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 311342   

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311342(US10155760, Example 199 | (S)-1-((2′,5-bis(d...)
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2020
Entry Details
US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311342(US10155760, Example 199 | (S)-1-((2′,5-bis(d...)
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311342(US10155760, Example 199 | (S)-1-((2′,5-bis(d...)
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2021
Entry Details
US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311342(US10155760, Example 199 | (S)-1-((2′,5-bis(d...)
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311342(US10155760, Example 199 | (S)-1-((2′,5-bis(d...)
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
US Patent

TargetAP2-associated protein kinase 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM311342(US10155760, Example 199 | (S)-1-((2′,5-bis(d...)
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 Cl prepared from 15 μl additions of enzyme and substrates (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
US Patent