BDBM312066 N-(2-Carbamoylpyridin-3-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide::US9649308, Example 41

SMILES NC(=O)c1ncccc1NC(=O)c1cnn2cccnc12

InChI Key InChIKey=FQQLYADVQADJOU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 312066   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM312066(US9649308, Example 41 | N-(2-Carbamoylpyridin-3-yl...)
Affinity DataIC50: 4.40E+3nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2019
Entry Details
Go to US Patent