BDBM312221 US9604926, Compound SN-249::US9724435, Compound SN-249

SMILES CC(O)c1ccc2n(CCCCN3CCN(CC3)c3ccc(F)cc3)c(=O)oc2c1

InChI Key InChIKey=DIVQRWSMHKWJJF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 312221   

TargetSigma intracellular receptor 2(Mouse)
The University of Mississippi

US Patent
LigandPNGBDBM312221(US9604926, Compound SN-249 | US9724435, Compound S...)
Affinity DataKi:  8.68nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetSigma intracellular receptor 2(Rat)
The University of Mississippi

US Patent
LigandPNGBDBM312221(US9604926, Compound SN-249 | US9724435, Compound S...)
Affinity DataKi:  8.68nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Mouse)
The University of Mississippi

US Patent
LigandPNGBDBM312221(US9604926, Compound SN-249 | US9724435, Compound S...)
Affinity DataKi:  609nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Mississippi

US Patent
LigandPNGBDBM312221(US9604926, Compound SN-249 | US9724435, Compound S...)
Affinity DataKi:  609nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent