BDBM313284 N-(3-(difluoromethyl)phenyl)-3-(5-(3-hydroxyoxetan-3-yl)-6-methoxypyridin-3-yl)-4-methylbenzamide::US10167279, Example 18

SMILES COc1ncc(cc1C1(O)COC1)-c1cc(ccc1C)C(=O)Nc1cccc(c1)C(F)F

InChI Key InChIKey=BEEUUPGEUAELJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313284   

LigandPNGBDBM313284(N-(3-(difluoromethyl)phenyl)-3-(5-(3-hydroxyoxetan...)
Affinity DataIC50: 600nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent