BDBM313515 N-(3'-(3-fluorooxetan-3- yl)-5'-(3-hydroxyoxetan- 3-yl)-6-methyl-[1,1'- biphenyl]-3-yl)-2- (trifluoromethyl)isonicotin- amide::US10167279, Example 135

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1cc(cc(c1)C1(F)COC1)C1(O)COC1

InChI Key InChIKey=LBAIDCWGSUTHAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313515   

LigandPNGBDBM313515(N-(3'-(3-fluorooxetan-3- yl)-5'-(3-hydroxyoxetan- ...)
Affinity DataIC50: 605nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
US Patent