BDBM313572 N-(3-(2,2-dimethyl-3- oxo-8-(tetrahydro-2H- pyran-4-yl)-3,4-dihydro- 2H-benzo[b][1,4]oxazin- 6-yl)-4-methylphenyl)-2- (trifluoromethyl) isonicotinamide::US10167279, Example 196

SMILES Cc1ccc(NC(=O)c2ccnc(c2)C(F)(F)F)cc1-c1cc2NC(=O)C(C)(C)Oc2c(c1)C1CCOCC1

InChI Key InChIKey=FEUHFBJSWSMHCZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 313572   

LigandPNGBDBM313572(N-(3-(2,2-dimethyl-3- oxo-8-(tetrahydro-2H- pyran-...)
Affinity DataIC50: 400nMAssay Description:Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent