BDBM314199 (2S,3R)-2-Amino-N—((S)-1-((6-bromo-2-methoxynaphthalen-1-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-3-hydroxybutanamide hydrochloride::US9611224, Example 11

SMILES COc1ccc2cc(Br)ccc2c1CN1c2ccccc2CC[C@H](NC(=O)[C@@H](N)[C@@H](C)O)C1=O

InChI Key InChIKey=YRFALZLFBOWGKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 314199   

TargetBaculoviral IAP repeat-containing protein 2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 314199BDBM314199((2S,3R)-2-Amino-N—((S)-1-((6-bromo-2-methoxyn...)
Affinity DataIC50: 3.88E+3nMAssay Description:The peptide AVPIAQKSEK-(ε-biotin)-OH (SEQ ID NO: 1) 1:2 TFA (Peptide A) was identified as a substrate for the TR-FRET assay by screening the 6× ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 314199BDBM314199((2S,3R)-2-Amino-N—((S)-1-((6-bromo-2-methoxyn...)
Affinity DataIC50: 5.48E+4nMAssay Description:The peptide AVPIAQKSEK-(ε-biotin)-OH (SEQ ID NO: 1) 1:2 TFA (Peptide A) was identified as a substrate for the TR-FRET assay by screening the 6× ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2019
Entry Details
US Patent