BDBM316143 2,5,8,11,14-pentaoxahexadecane-16-yl {4-[(6-{[2-(methylcarbamoyl)phenyl]thio}-1H-indazol-3-yl)ethynyl]phenyl}carbamate ::US9617222, Compound 18

SMILES CNC(=O)c1ccccc1Sc1ccc2c(n[nH]c2c1)C#Cc1ccc(NC(=O)OCCOCCOCCOCCOCCOC)cc1

InChI Key InChIKey=PXNIGPDIHFXANM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316143   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Senju Pharmaceutical

US Patent
LigandPNGBDBM316143(2,5,8,11,14-pentaoxahexadecane-16-yl {4-[(6-{[2-(m...)
Affinity DataIC50:  8nMAssay Description:Measurement of the kinase inhibitory activity of each compound produced in Examples was conducted using the Off-chip Mobility Shift Assay. For this t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent