BDBM316521 US11111242, Example 9::US9617258, Example 9

SMILES CC[C@H]1CC[C@H](CN1C(=O)C=C)Nc1ncnc2[nH]ccc12

InChI Key InChIKey=VBUKVIQTEXQNCT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 316521   

LigandPNGBDBM316521(US9617258, Example 9 | US11111242, Example 9 | US2...)
Affinity DataIC50: 0.400nMAssay Description:Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM316521(US9617258, Example 9 | US11111242, Example 9 | US2...)
Affinity DataIC50: 0.400nMAssay Description:JAK Caliper Enzyme Assay at 4 μM: Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

LigandPNGBDBM316521(US9617258, Example 9 | US11111242, Example 9 | US2...)
Affinity DataIC50: 0.400nMAssay Description:Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent

LigandPNGBDBM316521(US9617258, Example 9 | US11111242, Example 9 | US2...)
Affinity DataIC50: 53.9nMAssay Description:Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM316521(US9617258, Example 9 | US11111242, Example 9 | US2...)
Affinity DataIC50: 53.9nMAssay Description:JAK Caliper Enzyme Assay at 1 mM ATP: Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2022
Entry Details
US Patent

LigandPNGBDBM316521(US9617258, Example 9 | US11111242, Example 9 | US2...)
Affinity DataIC50: 53.9nMAssay Description:Test article was solubilized in dimethyl sulfoxide (DMSO) to a stock concentration of 30 mM. An 11-point half log dilution series was created in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent