BDBM316861 (3- cyanophenyl) methyl N-[3-[3- (2- oxopropanoylamino) phenyl]-1H- pyrrolo[2,3- b]pyridin-5- yl]carbamate::US9617260, Compound 20

SMILES CC(=O)C(=O)Nc1cccc(c1)-c1c[nH]c2ncc(NC(=O)OCc3cccc(c3)C#N)cc12

InChI Key InChIKey=QILJHYVMDWIYTO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 316861   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM316861((3- cyanophenyl) methyl N-[3-[3- (2- oxopropanoyla...)
Affinity DataIC50:  137nMAssay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Fluoresence...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent