BDBM317286 US9617273, Example 63

SMILES CC(C)(C)C(=O)ON[C@@H](Cc1ccccc1)C(=O)N1CC2=NNC(=O)c3cccc4[nH]c(c2c34)C1

InChI Key InChIKey=FWVKSMSZORBFPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 317286   

TargetPoly [ADP-ribose] polymerase 1(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 317286BDBM317286(US9617273, Example 63)
Affinity DataIC50: 100nMAssay Description:PARP-1 enzymatic assay was conducted using a method modified from HT F Homogeneous PARP Inhibition Assay Kit (Trevigen). 8.8 nM PARP-1 was pre-incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2019
Entry Details
US Patent