BDBM317459 6,8-dihydroxy-2-(4-hydroxyphenyl)-4-vinylisoquinolin-1(2H)-one::US9623021, 14m

SMILES Oc1ccc(cc1)-n1cc(C=C)c2cc(O)cc(O)c2c1=O

InChI Key InChIKey=PHJMFHYDJCTEFA-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 317459   

TargetEstrogen receptor beta(Human)
Gtx

US Patent
LigandPNGBDBM317459(US9623021, 14m | 6,8-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataKi:  7nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetEstrogen receptor(Human)
Gtx

US Patent
LigandPNGBDBM317459(US9623021, 14m | 6,8-dihydroxy-2-(4-hydroxyphenyl)...)
Affinity DataKi:  94nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent