BDBM317951 US10399976, Compound 104::US10807980, Compound 104::US11535614, Compound 104::US9624217, Compound 104

SMILES CCS(=O)(=O)N1CC(CNC(=O)c2cnc3[C@H](C(C)C)N(Cc4ccc(cc4)C(F)(F)F)Cc3c2)C1

InChI Key InChIKey=ZQXFHEHXIGNDAO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 317951   

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM317951(US9624217, Compound 104 | US10399976, Compound 104...)
Affinity DataKi:  550nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM317951(US9624217, Compound 104 | US10399976, Compound 104...)
Affinity DataKi:  550nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2021
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM317951(US9624217, Compound 104 | US10399976, Compound 104...)
Affinity DataKi:  550nMAssay Description:Compounds of the present invention were tested for ability to bind to RORγ in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM317951(US9624217, Compound 104 | US10399976, Compound 104...)
Affinity DataKi:  550nMAssay Description:Compounds of the present invention were tested for ability to bind to ROR gamma in a cell-free competition assay with commercially available radio-li...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/27/2020
Entry Details
US Patent