BDBM319542 US10173991, Example 607::methyl N-{4-[2- ({[(cyclopropyl- carbamoyl)methyl] carbamoyl} (methanesulfonyl) methyl)-5- (difluoromethoxy)- 1,3-benzothiazol- 6-yl]phenyl} carbamate

SMILES CS(=O)(=O)C(C(=O)NCC(=O)NC1CC1)c1nc2cc(OC(F)F)c(cc2s1)-c1ccc(NC(=O)CO)cc1

InChI Key InChIKey=NPOXWSYPNWRKCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 319542   

TargetEndothelial lipase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM319542(methyl N-{4-[2- ({[(cyclopropyl- carbamoyl)methyl]...)
Affinity DataIC50: 5nMAssay Description:Endothelial lipase (EL) and hepatic lipase (HL) activities were measured using a fluorescent substrate, A10070, (Invitrogen, CA) doped into an artifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
US Patent