BDBM320029 US10174016, Example 196::US10202369, Example 195::US10472354, Example 195

SMILES C[C@H](NC(=O)c1cc(OC2CCOCC2)cc(c1)-c1ncc(C)s1)c1nnc(s1)C(F)(F)F

InChI Key InChIKey=NWTVSPCFEGLAFO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 320029   

TargetP2X purinoceptor 3(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM320029(US10174016, Example 196 | US10202369, Example 195 ...)
Affinity DataIC50: 19nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM320029(US10174016, Example 196 | US10202369, Example 195 ...)
Affinity DataIC50: 19nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 2(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM320029(US10174016, Example 196 | US10202369, Example 195 ...)
Affinity DataIC50: 293nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 2(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM320029(US10174016, Example 196 | US10202369, Example 195 ...)
Affinity DataIC50: 293nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM320029(US10174016, Example 196 | US10202369, Example 195 ...)
Affinity DataIC50: 380nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
Go to US Patent

TargetP2X purinoceptor 3(Human)
Beyer Aktiengesellschaft

US Patent
LigandPNGBDBM320029(US10174016, Example 196 | US10202369, Example 195 ...)
Affinity DataIC50: 380nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent

TargetP2X purinoceptor 2/3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM320029(US10174016, Example 196 | US10202369, Example 195 ...)
Affinity DataIC50: 1.00E+4nMAssay Description:A fluorescent imaging plate reader (FILEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2020
Entry Details
Go to US Patent

TargetP2X purinoceptor 2/3(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM320029(US10174016, Example 196 | US10202369, Example 195 ...)
Affinity DataIC50: 1.00E+4nMAssay Description:A fluorescent imaging plate reader (FLEX/FLIPR station; Molecular Devices) was used to monitor intracellular calcium levels using the calcium-chelati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2019
Entry Details
Go to US Patent