BDBM320412 2-[(3-methylphenoxy)methyl]- 1H-pyrrolo[3,2-b]pyridine-7- carboxylic acid::US10174026, Example 74::US9738637, Example 74

SMILES Cc1cccc(OCc2cc3nccc(C(=O)O)c3[nH]2)c1

InChI Key InChIKey=SKIADERQBBOJPL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 320412   

TargetLysine-specific demethylase 5A(Human)
Celgene Quantical Research

US Patent
LigandChemical structure of BindingDB Monomer ID 320412BDBM320412(US10174026, Example 74 | 2-[(3-methylphenoxy)methy...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quantical Research

US Patent
LigandChemical structure of BindingDB Monomer ID 320412BDBM320412(US10174026, Example 74 | 2-[(3-methylphenoxy)methy...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantical Research

US Patent
LigandChemical structure of BindingDB Monomer ID 320412BDBM320412(US10174026, Example 74 | 2-[(3-methylphenoxy)methy...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent