BDBM320418 2-[(3,5-dimethylphenoxy)- methyl]-1H-pyrrolo[3,2-b]- pyridine-7-carboxylic acid::US10174026, Example 82::US9738637, Example 82

SMILES Cc1cc(C)cc(OCc2cc3nccc(C(=O)O)c3[nH]2)c1

InChI Key InChIKey=OEPKFVTWEHMPDT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 320418   

TargetLysine-specific demethylase 5A(Human)
Celgene Quantical Research

US Patent
LigandChemical structure of BindingDB Monomer ID 320418BDBM320418(US10174026, Example 82 | 2-[(3,5-dimethylphenoxy)-...)
Affinity DataIC50: 100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetLysine-specific demethylase 5B(Human)
Celgene Quantical Research

US Patent
LigandChemical structure of BindingDB Monomer ID 320418BDBM320418(US10174026, Example 82 | 2-[(3,5-dimethylphenoxy)-...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantical Research

US Patent
LigandChemical structure of BindingDB Monomer ID 320418BDBM320418(US10174026, Example 82 | 2-[(3,5-dimethylphenoxy)-...)
Affinity DataIC50: 550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2019
Entry Details
US Patent