BDBM32059 (3aR,6aS)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethoxyphenyl)-3a,6a-dihydropyrrol[3,4-d]isoxazole-4,6-quinone::(3aR,6aS)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethoxyphenyl)-3a,6a-dihydropyrrolo[3,4-d][1,2]oxazole-4,6-dione::(3aR,6aS)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(3,4-dimethoxyphenyl)-3a,6a-dihydropyrrolo[3,4-d]isoxazole-4,6-dione::MLS000042304::SMR000048763::cid_667377

SMILES COc1ccc(cc1OC)-c1[nH]oc2c(O)n(-c3ccc4OCCOc4c3)c(=O)c12

InChI Key InChIKey=IRXLMGDGJSMHRR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 32059   

TargetHeat shock protein HSP 90-alpha(Human)
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM32059((3aR,6aS)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(...)
Affinity DataIC50: 2.97E+4nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization based HTS assay has been developed and optimized for the identification of Hsp90 inhibitors by using tumor cell lysate Hs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2009
Entry Details
PCBioAssay