BDBM321142 US10174049, Example 9::US10385066, Example 9::US9738658, Example 9

SMILES CC(C)Oc1ccccc1-n1ccc2cc(ccc12)N1CCOc2ncnc(N)c2C1=O

InChI Key InChIKey=BPFNCLUZQMUHGH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 321142   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM321142(US10174049, Example 9 | US10385066, Example 9 | US...)
Affinity DataIC50:  9.70nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM321142(US10174049, Example 9 | US10385066, Example 9 | US...)
Affinity DataIC50:  9.70nMAssay Description:LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Glaxosmithkline

US Patent
LigandPNGBDBM321142(US10174049, Example 9 | US10385066, Example 9 | US...)
Affinity DataIC50:  9.70nMAssay Description:For inhibition of triacylglycerol product formation, 11 uL reactions were run in white Polyplate-384 (PerkinElmer6007300) starting with a 30 minute p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent