BDBM322515 (R)-6-(dimethylamino)-N-(1'-azaspiro[cyclopropane-1,2'-bicyclo[2.2.2]octan]-3'-yl)benzo[b]thiophene-2-carboxamide::US10183938, Compound (R)-269

SMILES CN(C)c1ccc2cc(sc2c1)C(=O)N[C@@H]1C2CCN(CC2)C11CC1

InChI Key InChIKey=APPVLPYVCCRTNB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 322515   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Axovant Sciences

US Patent
LigandPNGBDBM322515(US10183938, Compound (R)-269 | (R)-6-(dimethylamin...)
Affinity DataKi:  6.90E+3nMAssay Description:The ability of compounds to displace binding of radioactive ligands from human α7 nAChR was determined, as a measure of the affinity of the comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2019
Entry Details
US Patent